The Entourage Effect: Customizing Cannabinoid Product Profiles

The Entourage Effect: Customizing Cannabinoid Product Profiles

For those creating their own cannabis product lines, you've probably heard about something called the entourage effect. This theory lends additional support to those crafting specific formulations involving both cannabinoids and terpenes. Let's take a closer look at what the entourage effect is and how this can help you determine the right cannabinoid and terpene profiles for your CBD products.

What Is the Entourage Effect?

The entourage effect was first demonstrated in 1998 by Raphael Mechoulam and Shimon Ben-Shabat. This theory encompasses the belief that all the various compounds that are naturally occurring in cannabis work together in order to create amplified, unique effects and potential benefits. The hundreds of botanical compounds including cannabinoids and terpenes are believed to work synergetically together. It is believed that each one of these compounds has its own set of unique properties but these properties may be amplified or changed in the presence of other compounds.

Studies have highlighted the entourage effect, showing that there may be better therapeutic promise when combining these compounds. For instance, in this 2010 study, patients experiencing cancer-related pain were given either pure THC extract or an extract that had equal parts THC and CBD. The result of this particular study was that the patients given the THC and CBD combination reported having less pain.

Since there are hundreds of cannabinoids and terpenes that make up the profile of any cannabis strain, this diversity offers endless possibilities when it comes to different synergies that may be available. This theory supports the wide range of promising therapeutic benefits that differ from strain to strain. The entourage effect is currently being studied for its potential benefits for a variety of conditions including mood and anxiety disorders.

CBD Isolate vs. Broad and Full-Spectrum Products

Even though the entourage effect may offer further medicinal benefits for broad and full-spectrum products, there are still many reasons why having a CBD isolate product would be beneficial for your product line. Isolates offer the opportunity to enjoy cannabis products without having to worry about absorbing any specific cannabinoids or terpenes that you might not be interested in.

Formulating Broad and Full-Spectrum Products

With the entourage effect in mind, you can map out various cannabinoids and terpenes for supporting your product's intended purpose. For example, if you're interested in developing a sleep CBD product, you can research CBN, linalool, and other potentially sedating cannabis compounds. Another route would be finding specific hemp strains with the cannabinoid and terpene profile that you're interested in and having your products derived from this cultivar.

Work With the Nation's Leading White Label CBD Manufacturer

Tenacious Labs Manufacturing is honored to be the leading white label CBD manufacturer serving the nation. Our turnkey services include custom formulations - our team is happy to help you formulate your next cannabis product with the entourage effect in mind. For more information regarding the entourage effect, please contact us!